All vasoactive medication are mixed with 5% Dextrose and are ALWAYS administered via a Central Venous Catheter (CVC).
Vasoactive medications can be mixed in 50ml (as below) and given via a syringe driver, or strength doubled and mixed in 100ml bag and delivered via a volumetric pump (discuss with Registered Nurse caring for patient).
Drug | Concentration | Infusion Rate |
Propofol | 10mg/ml | Run at 5-25 ml/hr |
Noradrenaline | 2mg/50ml | Run at 0-15 ml/hr |
Phenylephrine | 10mg/50ml | Run at 0.15 ml/hr |
Adrenaline | 3 mg/50ml 1mg/50ml (OT) | Run at 0-15 ml/hr |
Dopamine | 200mg/50ml | Run at 2-10 mls/hr |
Dobutamine | 250mg/50ml | Run at 1-10 mls/hr |
GTN | 50mg/50ml 10mg/50ml (OT) | Run at 0-10 ml/hr Run at 0-40 ml/hr |
Milrinone | 20mg/50ml | Loading dose given in OT Run at 375-0.75mcg/kg/min |
Amiodarone | 300mg/100ml | Loading dose Run over 30-60 min |
| 900mg/500ml | Run over 24 hrs If in SR oral for 6 weeks |
Actrapid | 50iu/50ml NaCl | As per SPRINT guidelines |
Heparin | 5000IU/50ml NaCl | As per desired APTT Not routinely used post op |