Hospitals & Services
Localisation of suspected parathyroid adenoma. It is not a screening test for hyperparathyroidism.
Sestamibi is actively taken up by parathyroid adenomata and has a slow washout from these lesions compared to normal parathyroid tissue. The scan is normally done in conjunction with a technetium thyroid scan because thyroid adenomas may also show increased retention of Sestamibi.
Preparation and Procedure:
The technetium thyroid scan is usually performed 2 – 3 days before the parathyroid study.
Parathyroid scans involve early and late acquisitions over a period of 2.5 hours.
99mTc-Sestamibi parathyroid imaging can be useful in the preoperative detection and localisation of parathyroid adenomas in patients having proven hyperparathyroidism (sensitivity of 90%). SPECT/CT provides topographic correlation with adjacent anatomical structures; this imaging technique can identify a single adenoma, multiple adenomas, ectopic adenomas or hyperplastic glands.